MAP3K7 polyclonal antibody
产品名称： MAP3K7 polyclonal antibody
英文名称： MAP3K7 polyclonal antibody
产品编号： PAB7038
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of MAP3K7.
- Immunogen:
- A synthetic peptide corresponding to internal region of human MAP3K7.
- Sequence:
- C-AELDQDEKDQQNT
- Host:
- Goat
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognise isoform A (NP_003179.1) and isoform B (NP_663304.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:8000)
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Transfected lysate)
- HEK293 lysate (10 ug protein in RIPA buffer) overexpressing human MAP3K7 with DYKDDDDK tag probed with MAP3K7 polyclonal antibody (Cat # PAB7038) (1 ug/mL) in Lane 1 and probed with anti- DYKDDDDK Tag (1/3000) in lane 3. Mock-transfected HEK293 probed with MAP3K7 polyclonal antibody (Cat # PAB7038) (1 mg/mL) in Lane 2. Primary incubations were for 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 6885
- Protein Accession#:
- NP_003179.1;NP_663304.1
- Gene Name:
- MAP3K7
- Gene Alias:
- TAK1,TGF1a
- Gene Description:
- mitogen-activated protein kinase kinase kinase 7
- Omim ID:
- 602614
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- OTTHUMP00000016870,OTTHUMP00000016871,OTTHUMP00000016872,OTTHUMP00000016873,TGF-beta activated kinase 1,transforming growth factor-beta-activated kinase 1
- Interactome
