BLNK monoclonal antibody, clone 5G9
产品名称： BLNK monoclonal antibody, clone 5G9
英文名称： BLNK monoclonal antibody, clone 5G9
产品编号： MAB10505
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant BLNK.
- Immunogen:
- Recombinant protein corresponding to human BLNK.
- Host:
- Mouse
- Theoretical MW (kDa):
- 68
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis using BLNK monoclonal antibody, clone 5G9 (Cat # MAB10505) against NIH/3T3 (1) and BCBL-1 (2) cell lysate.
- Western Blot (Recombinant protein)
- Western blot analysis using BLNK monoclonal antibody, clone 5G9 (Cat # MAB10505) against human BLNK (aa: 34-216) recombinant protein. (Expected MW is 60 kDa).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using BLNK monoclonal antibody, clone 5G9 (Cat # MAB10505) with DAB staining.
- Entrez GeneID:
- 29760
- Gene Name:
- BLNK
- Gene Alias:
- BASH,BLNK-S,LY57,MGC111051,SLP-65,SLP65
- Gene Description:
- B-cell linker
- Omim ID:
- 604515
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- B cell linker protein,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,OTTHUMP00000020167,Src homology 2 domain-containing leukocyte protein of 65 kDa
- Interactome
- Related Disease