KDM5B monoclonal antibody (M02), clone 1G10
产品名称： KDM5B monoclonal antibody (M02), clone 1G10
英文名称： KDM5B monoclonal antibody (M02), clone 1G10
产品编号： H00010765-M02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant KDM5B.
- Immunogen:
- KDM5B (NP_006609, 231 a.a. ~ 319 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- AKRMRAEAMNIKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGN
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.53 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Jumonji/ARID1 B (JARID1B) Protein Promotes Breast Tumor Cell Cycle Progression through Epigenetic Repression of MicroRNA let-7e.
Mitra D, Das PM, Huynh FC, Jones FE.J Biol Chem. 2011 Nov 25;286(47):40531-5. Epub 2011 Oct 3.
- 2.
- Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Hayami S, Yoshimatsu M, Veerakumarasivam A, Unoki M, Iwai Y, Tsunoda T, Field HI, Kelly JD, Neal DE, Yamaue H, Ponder BA, Nakamura Y, Hamamoto R.Mol Cancer. 2010 Mar 13;9:59.
- 3.
- JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer.
Xiang Y, Zhu Z, Han G, Ye X, Xu B, Peng Z, Ma Y, Yu Y, Lin H, Chen AP, Chen CD.Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19226-31. Epub 2007 Nov 28.
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to KDM5B on formalin-fixed paraffin-embedded human colon. [antibody concentration 1 ug/ml]
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to KDM5B on HeLa cell . [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged KDM5B is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 10765
- GeneBank Accession#:
- NM_006618
- Protein Accession#:
- NP_006609
- Gene Name:
- KDM5B
- Gene Alias:
- FLJ10538,FLJ12459,FLJ12491,FLJ16281,FLJ23670,KDM5B,PLU-1,PUT1,RBBP2H1A
- Gene Description:
- jumonji, AT rich interactive domain 1B
- Omim ID:
- 605393
- Gene Ontology:
- Hyperlink
- Other Designations:
- OTTHUMP00000038815,RBP2-like,putative DNA/chromatin binding motif,retinoblastoma-binding protein 2, homolog 1A
- Related Disease