PRKAG2 monoclonal antibody (M01), clone 3C4
产品名称: PRKAG2 monoclonal antibody (M01), clone 3C4
英文名称: PRKAG2 monoclonal antibody (M01), clone 3C4
产品编号: H00051422-M01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PRKAG2.
- Immunogen:
- PRKAG2 (AAH20540, 191 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- AFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAE
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of PRKAG2 expression in transfected 293T cell line by PRKAG2 monoclonal antibody (M01), clone 3C4.
Lane 1: PRKAG2 transfected lysate (Predicted MW: 37.5 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunofluorescence
- enlarge this image
- Immunofluorescence of monoclonal antibody to PRKAG2 on HeLa cell . [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PRKAG2 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 51422
- GeneBank Accession#:
- BC020540
- Protein Accession#:
- AAH20540
- Gene Name:
- PRKAG2
- Gene Alias:
- AAKG,AAKG2,CMH6,H91620p,WPWS
- Gene Description:
- protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- Gene Ontology:
- Hyperlink
- Gene Summary:
- AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- AMP-activated protein kinase gamma2 subunit,AMPK gamma2
- Related Disease
- Atherosclerosis
- Calcinosis
- Cardiomegaly
- Cardiomyopathy, Dilated
- Cardiomyopathy, Hypertrophic, Familial
- Cardiovascular Diseases
- Colonic Neoplasms
- Coronary Artery Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Drug Toxicity
- Edema
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Insulin Resistance
- Kidney Failure, Chronic
- Rectal Neoplasms
- Tobacco Use Disorder