CILP polyclonal antibody
产品名称： CILP polyclonal antibody
英文名称： CILP polyclonal antibody
产品编号： PAB7075
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of CILP.
- Immunogen:
- A synthetic peptide corresponding to human CILP.
- Sequence:
- C-NYRRTDHEDPRVK
- Host:
- Goat
- Theoretical MW (kDa):
- 133
- Reactivity:
- Rat
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:128000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
Seki S, Kawaguchi Y, Chiba K, Mikami Y, Kizawa H, Oya T, Mio F, Mori M, Miyamoto Y, Masuda I, Tsunoda T, Kamata M, Kubo T, Toyama Y, Kimura T, Nakamura Y, Ikegawa S.Nat Genet. 2005 Jun;37(6):607-12. Epub 2005 May 1.
- Entrez GeneID:
- 8483
- Protein Accession#:
- NP_003604.2
- Gene Name:
- CILP
- Gene Alias:
- CILP-1,HsT18872
- Gene Description:
- cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for 2 different proteins, namely CILP and a homolog of NTPPHase, however later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. One isoform of the protein, CILP-1, functions as an IGF-1 antagonist. [provided by RefSeq
- Other Designations:
- cartilage intermediate layer protein,cartilage intermediate layer protein 1 C1,cartilage intermediate layer protein 1 C2
- Related Disease